作者
Michael R MacDonald, Derek T Connelly, Nathaniel M Hawkins, Tracey Steedman, John Payne, Morag Shaw, Martin Denvir, Sai Bhagra, Sandy Small, William Martin, John JV McMurray, Mark C Petrie
发表日期
2011/5/1
期刊
Heart
卷号
97
期号
9
页码范围
740-747
出版商
BMJ Publishing Group Ltd
简介
Objective
To determine whether or not radiofrequency ablation (RFA) for persistent atrial fibrillation in patients with advanced heart failure leads to improvements in cardiac function.
Setting
Patients were recruited from heart failure outpatient clinics in Scotland.
Design and intervention
Patients with advanced heart failure and severe left ventricular dysfunction were randomised to RFA (rhythm control) or continued medical treatment (rate control). Patients were followed up for a minimum of 6 months.
Main outcome measure
Change in left ventricular ejection fraction (LVEF) measured by cardiovascular MRI.
Results
22 patients were randomised to RFA and 19 to medical treatment. In the RFA group, 50% of patients were in sinus rhythm at the end of the study (compared with none in the medical treatment group). The increase in cardiovascular magnetic resonance (CMR) LVEF in the RFA group was 4.5±11.1% compared …
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MR MacDonald, DT Connelly, NM Hawkins… - Heart, 2011