作者
Julie Péron, Didier Grandjean, Florence Le Jeune, Paul Sauleau, Claire Haegelen, Dominique Drapier, Tiphaine Rouaud, Sophie Drapier, Marc Vérin
发表日期
2010/3/1
期刊
Neuropsychologia
卷号
48
期号
4
页码范围
1053-1062
出版商
Pergamon
简介
The recognition of facial emotions is impaired following subthalamic nucleus (STN) deep brain stimulation (DBS) in Parkinson's disease (PD). These changes have been linked to a disturbance in the STN's limbic territory, which is thought to be involved in emotional processing. This was confirmed by a recent PET study where these emotional modifications were correlated with changes in glucose metabolism in different brain regions, including the amygdala and the orbitofrontal regions that are well known for their involvement in emotional processing. Nevertheless, the question as to whether these emotional changes induced by STN DBS in PD are modality-specific has yet to be answered. The objective of this study was therefore to examine the effects of STN DBS in PD on the recognition of emotional prosody. An original emotional prosody paradigm was administered to twenty-one post-operative PD patients …
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