作者
Ida Rask Moustsen, Signe Benzon Larsen, Anne Katrine Duun-Henriksen, Anne Tjønneland, Susanne K Kjær, Klaus Brasso, Christoffer Johansen, Susanne Oksbjerg Dalton
发表日期
2019/5
期刊
British journal of cancer
卷号
120
期号
11
页码范围
1067
出版商
Nature Publishing Group
简介
Background
The effect of lifestyle, anthropometry and cardiovascular risk factors on cardiovascular disease in men with prostate cancer (PCa) remains unclear.
Methods
Using a population-based cohort of 25,436 Danish, cancer-free men aged 50–64 years, we obtained information on self-reported pre-cancer lifestyle, objectively measured anthropometry and cardiovascular risk factors, and linked them to national health registers for information on major cardiovascular outcomes. We assessed hazard ratios (HRs) of incident acute myocardial infarction (MI), ischaemic stroke (IS) and heart failure (HF) among 1546 men diagnosed with PCa treated with first-line active surveillance, watchful waiting, intended curative or palliative treatment compared with PCa-free men during 18 years of follow-up.
Results
Men who received first-line palliative treatment had higher rates of IS and HF with adjusted HRs of 2.09 (95% CI 1.49 …
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