作者
Alessandra Tucci, Samantha Ferrari, Chiara Bottelli, Erika Borlenghi, Monica Drera, Giuseppe Rossi
发表日期
2009/10/1
期刊
Cancer: Interdisciplinary International Journal of the American Cancer Society
卷号
115
期号
19
页码范围
4547-4553
出版商
Wiley Subscription Services, Inc., A Wiley Company
简介
BACKGROUND
The authors set out to analyze if a simple comprehensive geriatric assessment (CGA) could objectively identify elderly patients with diffuse large cell lymphoma (DLCL) who can be effectively treated with anthracycline‐containing immunochemotherapy.
METHODS
CGA was performed in 84 consecutive patients with DLCL aged >65 years and diagnosed at a single institution. Treatment with curative versus palliative intent was chosen according to clinical judgment. Cyclophosphamide, hydroxydaunomycin, Oncovin (vincristine), and prednisone (CHOP) or CHOP‐like regimens were given to 62 (74%) patients. The outcome of patients was analyzed according to both the treatment received and the results of CGA.
RESULTS
According to CGA, 42 (50%) patients were classified as “fit.” They were younger (P < .0001) and had less frequent systemic symptoms (P = .03). These patients received …
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A Tucci, S Ferrari, C Bottelli, E Borlenghi, M Drera… - Cancer: Interdisciplinary International Journal of the …, 2009