作者
Manish Gautam, Santanu Saha, Sarang Bani, A Kaul, Sanjay Mishra, Dada Patil, NK Satti, KA Suri, Sunil Gairola, K Suresh, Suresh Jadhav, GN Qazi, Bhushan Patwardhan
发表日期
2009/1/21
期刊
Journal of ethnopharmacology
卷号
121
期号
2
页码范围
241-247
出版商
Elsevier
简介
ETHNOPHARMACOLOGICAL RELEVANCE
Roots of Asparagus racemosus Willd (Shatavari in vernacular) are widely used in Ayurveda as Rasayana for immunostimulation, galactogogue as also in treatment of conditions like ulcers and cancer. Various studies have indicated immunomodulatory properties of Shatavari root extracts and formulations.
AIM OF THE STUDY
To study the effect of standardized Asparagus racemosus root aqueous extract (ARE) on systemic Th1/Th2 immunity of SRBC sensitized animals.
MATERIALS AND METHODS
We used HPTLC to quantify steroidal saponins (Shatavarin IV, Immunoside®) and flow cytometry to study effects of ARE on Th1/Th2 immunity. SRBC specific antibody titres and DTH responses were also monitored as markers of Th2 and Th1 responses, respectively. We also studied lymphocyte proliferation. Cyclosporin, cyclophosphamide and levamisole were used as …
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