作者
Daniel L Baker, Patton Morrison, Brigitte Miller, Caroline A Riely, Betsy Tolley, Anneke M Westermann, Johannes MG Bonfrer, Evert Bais, Wouter H Moolenaar, Gabor Tigyi
发表日期
2002/6/19
期刊
Jama
卷号
287
期号
23
页码范围
3081-3082
出版商
American Medical Association
简介
Methods
Using liquid chromotography/mass spectroscopy, 5 we measured plasma concentrations of 5 individual LPA acyl species (LPA 16: 0, 18: 2, 18: 1, 18: 0, and 20: 4, which comprise more than 90% of total plasma LPA) in 32 patients with ovarian cancer and 32 healthy control subjects (mean [SD] age, 53 [13] and 42 [12] years, respectively). We also determined LPA concentrations in samples of ascites and pleural fluid from patients with malignant effusions related to their ovarian cancer, as part of a previous study. 2 All patients provided informed consent in accordance with the policies of our institutional review board.
引用总数
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DL Baker, P Morrison, B Miller, CA Riely, B Tolley… - Jama, 2002