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The occurrence of metal tolerant and antibiotic resistant organisms was investigated in tannery effluent. Seventy-seven isolates comprising heterotrophs (41) and coliforms (36) which were tolerant to chromate level of >50 μg / ml were selected for detailed study. The majority of the coliforms were resistant to higher levels of chromate (200 μg/ml) whereas around 3% of the heterotrophs were resistant to Cr⁶⁺ at a level of >150 μg / ml . All chromate tolerant heterotrophs were also tolerant to Cu²⁺ (100%) whereas only 58.53% coliforms were tolerant to Cu²⁺. Except in the case of Cd²⁺ a higher number of heterotrophs were found tolerant to other heavy metals tested. Both groups of isolates were found sensitive to mercury. Resistance to cephaloridine was more abundant (P<0.001) in coliforms as compared to heterotrophs. On the other hand a significantly higher number (P<0.01) of heterotrophs showed resistance to …