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The Evidence for HIV Prevention in Southern Africa research programme specifically reviewed definitions of child, adolescent, youth, and adult used in research and health programming in eastern and southern Africa. 2 This review supports defining adolescence as 10–24 years, on the basis of realities of adolescence and youth in substantially different, resource-limited contexts. Young people still adopt adult roles early in life, yet face diverse and changing epidemiological, social, and economic threats to health different from those of children and adults. While 20–24 year olds are substantially different to 10–19 year olds, their health challenges are also part of a continuum of risks and intervention opportunities that starts in the younger group. The review, like Janet McDonagh and colleagues, 3 also reiterated the need for a unified approach to categorising the 10–24 year age group to reduce confusing …