作者
TA Mathew, TN Ovsyanikova, SS Shin, I Gelmanova, DA Balbuena, S Atwood, GG Peremitin, AK Strelis, MB Murray
发表日期
2006/8/1
期刊
The International Journal of Tuberculosis and Lung Disease
卷号
10
期号
8
页码范围
857-863
出版商
International Union Against Tuberculosis and Lung Disease
简介
SETTING
Tuberculosis (TB) incidence and mortality in Russia have risen dramatically over the past 15 years.
OBJECTIVE
To identify risk factors and causes of death among TB patients in Russia.
DESIGN
A retrospective study conducted to determine the risk factors and causes of death in patients receiving TB therapy in Tomsk, Siberia.
RESULTS
Of 1916 patients who initiated treatment between 1 January 2002 and 31 December 2003, 183 (9.6%) died during treatment, 38 (21%) in the first week of therapy. Twenty-five per cent of deaths were not directly attributable to TB. Risk factors for death included older age, previous treatment for TB, multidrug resistance and alcoholism.
CONCLUSIONS
The high death rate during TB treatment observed in this cohort likely reflects an increased risk of dying not only from TB, but also from comorbid conditions, such as alcoholism and cardiovascular disease. Overall, alcoholism …
引用总数
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