作者
Mohamed Abdelgadir Adam, John Pura, Paolo Goffredo, Michaela A Dinan, Terry Hyslop, Shelby D Reed, Randall P Scheri, Sanziana A Roman, Julie A Sosa
发表日期
2015/1/1
期刊
The Journal of Clinical Endocrinology & Metabolism
卷号
100
期号
1
页码范围
115-121
出版商
Oxford University Press
简介
Context
Papillary thyroid cancer (PTC) patients <45 years old are considered to have an excellent prognosis; however, current guidelines recommend total thyroidectomy for PTC tumors >1.0 cm, regardless of age.
Objective
Our objective was to examine the impact of extent of surgery on overall survival (OS) in patients <45 years old with stage I PTC of 1.1 to 4.0 cm.
Design, Setting, and Patients
Adult patients <45 years of age undergoing surgery for stage I PTC were identified from the National Cancer Data Base (NCDB, 1998–2006) and the Surveillance, Epidemiology, and End Results dataset (SEER, 1988–2006).
Main Outcome Measure
Multivariable modeling was used to compare OS for patients undergoing total thyroidectomy vs lobectomy.
Results
In total, 29 522 patients in NCDB (3151 lobectomy, 26 371 …
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M Abdelgadir Adam, J Pura, P Goffredo, MA Dinan… - The Journal of Clinical Endocrinology & Metabolism, 2015