作者
Weijian Huang, Shengjie Wu, Pugazhendhi Vijayaraman, Lan Su, Xueying Chen, Bingni Cai, Jiangang Zou, Rongfang Lan, Guosheng Fu, Guangyun Mao, Kenneth A Ellenbogen, Zachary I Whinnett, Roderick Tung
发表日期
2020/7/1
期刊
Clinical Electrophysiology
卷号
6
期号
7
页码范围
849-858
出版商
American College of Cardiology Foundation
简介
Objectives
The aim of this study was to assess the feasibility and efficacy of left bundle branch pacing (LBBP) using a novel intraseptal technique to deliver cardiac resynchronization therapy (CRT) in patients with left bundle branch block (LBBB) and nonischemic cardiomyopathy.
Background
His bundle pacing to correct LBBB is a viable alternative approach to achieve CRT but is limited by suboptimal lead delivery and high thresholds.
Methods
This was a prospective, multicenter study performed between June 2017 and August 2018 at 6 centers. Patients with nonischemic cardiomyopathy, complete LBBB, and left ventricular ejection fractions (LVEFs) ≤50% who had indications for CRT and/or ventricular pacing in whom LBBP was attempted were included. Success rates, QRS duration, LVEF, left ventricular end-systolic volume, and improvement in functional class were assessed.
Results
LBBP was …
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