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Chemotherapy‐induced nausea and vomiting (CINV) are major adverse effects of chemotherapy. Ginger has been used in postoperative and pregnancy‐induced nausea and vomiting. Data on its utility in reducing CINV in children and young adults are lacking.

Sixty chemotherapy cycles of cisplatin/doxorubicin in bone sarcoma patients were randomized to ginger root powder capsules or placebo capsules as an additional antiemetic to ondensetron and dexamethasone in a double‐blind design. Acute CINV was defined as nausea and vomiting occurring within 24 hr of start of chemotherapy (days 1–4) and delayed CINV as that occurring after 24 hr of completion of chemotherapy (days 5–10). CINV was evaluated as per Edmonton's Symptom Assessment Scale and National Cancer Institute criteria respectively.

Acute moderate to severe nausea was observed in 28/30 …