作者
Katie Maurer, Haesook T Kim, Heather M Garrity, Deborah Liney, Corey Cutler, Joseph H Antin, John Koreth, Jerome Ritz, Roman M Shapiro, Rizwan Romee, Vincent T Ho, Mahasweta Gooptu, Robert J Soiffer, Catherine J Wu, Sarah Nikiforow
发表日期
2023/6/6
期刊
Blood Advances
卷号
7
期号
11
页码范围
2431
出版商
The American Society of Hematology
简介
Allogeneic hematopoietic stem cell transplantation (allo-HSCT) typically utilizes fresh donor bone marrow (BM) or peripheral blood stem cells (PBSCs) because of concerns that cryopreservation may negatively impact patient outcomes. 1 The COVID-19 pandemic spurred renewed interest in the impact of cryopreservation after the National Marrow Donor Program (NMDP) mandated cryopreservation of unrelated donor (URD) PBSCs between March and August 2020. 2
Although the cryopreservation mandate was lifted after August 2020, heterogeneity in cryopreservation practices among transplant centers remains. Moreover, data on long-term outcomes of using such products are scarce. We previously reported lack of difference in 6-month overall survival (OS), progression free survival (PFS), relapse, and nonrelapse mortality (NRM) for adult recipients of cryopreserved PBSCs compared with those of fresh URD …
学术搜索中的文章
K Maurer, HT Kim, HM Garrity, D Liney, C Cutler… - Blood Advances, 2023