作者
Eugenia Resmini, Alicia Santos, Beatriz Gomez-Anson, Yolanda Vives, Patricia Pires, Iris Crespo, Maria J Portella, Manel de Juan-Delago, Maria-Jose Barahona, Susan M Webb
发表日期
2012/2/1
期刊
The Journal of Clinical Endocrinology & Metabolism
卷号
97
期号
2
页码范围
663-671
出版商
Oxford University Press
简介
Context
Cushing's syndrome (CS) affects cognition and memory.
Objective
Our objective was to evaluate memory and hippocampal volumes (HV) on 3-tesla magnetic resonance imaging (3T MRI) in CS patients and controls.
Patients and Methods
Thirty-three CS patients (11 active, 22 cured) and 34 controls matched for age, sex, and education underwent Rey Auditory Verbal Learning Test and Rey-Osterrieth Complex Figure memory tests. Gray matter and HV were calculated on 3T MRI, using FreeSurfer image analyses software.
Results
No differences in HV were observed between active and cured CS or controls. Memory performance was worse in CS patients than controls (P < 0.04 in active; P < 0.03 in cured CS) but did not differ among CS groups, which were therefore analyzed together; they performed worse for verbal (P = 0.02) and …
学术搜索中的文章
E Resmini, A Santos, B Gomez-Anson, Y Vives, P Pires… - The Journal of Clinical Endocrinology & Metabolism, 2012