作者
Caren G Solomon, Walter C Willett, Vincent J Carey, Janet Rich-Edwards, David J Hunter, Graham A Colditz, Meir J Stampfer, Frank E Speizer, Donna Spiegelman, JoAnn E Manson
发表日期
1997/10/1
期刊
Jama
卷号
278
期号
13
页码范围
1078-1083
出版商
American Medical Association
简介
Context
—Gestational diabetes mellitus (GDM) affects 3% to 5% of pregnancies. Knowledge of risk factors for GDM is needed to identify possible preventive strategies.
Objective
—To assess whether recognized determinants of non-insulindependent diabetes mellitus also may be markers for increased risk of GDM.
Design
—Prospective cohort study.
Setting
—The Nurses' Health Study II, which involves female US nurses aged 25 to 42 years at entry.
Participants
—The analyses included 14613 women without previous GDM or other known diabetes who reported a singleton pregnancy between 1990 and 1994. Of these women, 722 (4.9%) reported a new diagnosis of GDM.
Main Outcome Measure
Self-report of GDM, validated by medical record review in a subset.
Results
—multivariate analyses including age, pregravid body mass index (BMI), and other GDM risk factors, the risk for GDM increased significantly with …
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