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This descriptive study on onchocerciasis was conducted among 72 randomly selected inhabitants of a rural community, in Oyo State, Nigeria, during the planting season between the months of April and June. Demographic information, the length of time the subjects had lived in the study area and previous treatments received for the disease (if any), were obtained using a questionnaire. The effect of ivermectin administration was investigated in the study area. The objectives of the study were to identify the age brackets and occupation of the inhabitants at high risk, and to determine the severity of infection in the study area. Four skin snips were obtained from both scapular regions and the two gluteal folds of each participant, and examined for microfilaria of Onchocerca volvulus. Data were analyzed using the SPSS version 12.0, involving descriptive statistics, frequencies, percentages and the student t-test to test for …