作者
Shirin Farahyar, Samira Izadi, Elham Razmjou, Mehraban Falahati, Maryam Roudbary, Mahtab Ashrafi-Khozani, Saham Ansari, Azam Fattahi, Zahra Ghahri-Mobaser, Maryam Rahimi
发表日期
2020/3/1
期刊
Heliyon
卷号
6
期号
3
出版商
Elsevier
简介
The Candida (C.) albicans complex includes C. albicans, C. dubliniensis, C. stellatoidea, and C. africana, with the last mentioned as an important emerging agent of vulvovaginal candidiasis (VVC). The aim of the study was to identify C. africana and C. dubliniensis and assess their drug susceptibility in vaginitis. One-hundred Candida isolates of the C. albicans complex from women diagnosed with vaginitis and from vaginal samples in the culture collection of a medical mycology laboratory were examined. Species of the C. albicans complex were identified with conventional and molecular methods using polymerase chain reaction (PCR) for amplification and sequencing of the internal transcribed spacer (ITS) region, PCR for partial amplification of hyphal wall protein 1 (HWP1) gene and duplex PCR. The effects of antifungal drugs were evaluated according to standard broth microdilution protocols.
Ninety-seven C …
引用总数
2020202120222023202447835