作者
Darryl C De Vivo, Rosario R Trifiletti, Ronald I Jacobson, Gabriel M Ronen, Ramin A Behmand, Sami I Harik
发表日期
1991/9/5
期刊
New England Journal of Medicine
卷号
325
期号
10
页码范围
703-709
出版商
Massachusetts Medical Society
简介
GLUCOSE (D-glucose) is an essential fuel for the brain and many other tissues. Five glucose-transporter proteins facilitate the diffusion of glucose across lipophilic plasma membranes.1 2 3 This process is saturable and stereospecific, but it is not concentrative, energy dependent, or influenced by sodium. In humans, the erythrocyte glucose transporter (type 1 glucose transporter) has been studied most extensively. It accounts for 2 to 5 percent of the erythrocyte-membrane protein and seems to be identical in molecular weight and antigenic properties to the glucose transporters in the endothelial cells of brain capillaries.4 5 6 7 Brain capillaries contain large amounts of messenger RNA for the . . .
引用总数
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DC De Vivo, RR Trifiletti, RI Jacobson, GM Ronen… - New England Journal of Medicine, 1991