作者
Marc Beltempo, Pia Wintermark, Brigitte Lemyre, Wissam Shalish, Andrea Martel-Bucci, Michael Narvey, Eugene H Ng, Mireille Guillot, Prakesh S Shah, Jaideep Kanungo, Joseph Ting, Zenon Cieslak, Rebecca Sherlock, Wendy Yee, Jennifer Toye, Carlos Fajardo, Zarin Kalapesi, Koravangattu Sankaran, Sibasis Daspal, Mary Seshia, Ruben Alvaro, Amit Mukerji, Orlando Da Silva, Chuks Nwaesei, Kyong-Soon Lee, Michael Dunn, Kimberly Dow, Ermelinda Pelausa, Keith Barrington, Anie Lapoint, Christine Drolet, Bruno Piedboeuf, Martine Claveau, Valerie Bertelle, Edith Masse, Roderick Canning, Hala Makary, Cecil Ojah, Luis Monterrosa, Julie Emberley, Jehier Afifi, Andrzej Kajetanowicz, Shoo K Lee
发表日期
2019/11/1
期刊
The Journal of pediatrics
卷号
214
页码范围
27-33. e3
出版商
Mosby
简介
Objective
To identify risk factors for severe neurologic injury (intraventricular hemorrhage grade 3 or greater and/or periventricular leukomalacia) diagnosed by ultrasound scan of the head among infants born at 300-326 weeks of gestation and compare different screening strategies.
Study design
This was a retrospective cohort study of infants born at 300-326 weeks or >326 weeks of gestation with a birth weight <1500 g admitted to neonatal intensive care units in the Canadian Neonatal Network from 2011 to 2016. Stepwise logistic regression analysis was used to identify significant risk factors and calculate aORs and 95% CIs. Risk factor-based screening strategies were compared.
Results
The rate of severe neurologic injury was 3.1% among infants screened (285/9221). Significant risk factors included singleton birth (aOR 1.96, 95% CI 1.35-2.85), 5-minute Apgar <7 (aOR 1.81, 95% CI 1.30-2.50), mechanical …
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M Beltempo, P Wintermark, B Lemyre, W Shalish… - The Journal of pediatrics, 2019