作者
Mahmoud T KhalafAllah, Linda M Zangwill, James Proudfoot, Evan Walker, Christopher A Girkin, Massimo A Fazio, Robert N Weinreb, Christopher Bowd, Sasan Moghimi, C Gustavo De Moraes, Jeffrey M Liebmann, Lyne Racette
发表日期
2024/3/1
期刊
American Journal of Ophthalmology
卷号
259
页码范围
7-14
出版商
Elsevier
简介
PURPOSE
To evaluate the diagnostic accuracy of retinal nerve fiber layer thickness (RNFLT) by spectral-domain optical coherence tomography (OCT) in primary open-angle glaucoma (POAG) in eyes of African (AD) and European descent (ED).
DESIGN
Comparative diagnostic accuracy analysis by race.
PARTICIPANTS
379 healthy eyes (125 AD and 254 ED) and 442 glaucomatous eyes (226 AD and 216 ED) from the Diagnostic Innovations in Glaucoma Study and the African Descent and Glaucoma Evaluation Study.
METHODS
Spectralis (Heidelberg Engineering GmbH) and Cirrus (Carl Zeiss Meditec) OCT scans were taken within 1 year from each other.
MAIN OUTCOME MEASURES
Diagnostic accuracy of RNFLT measurements.
RESULTS
Diagnostic accuracy for Spectralis-RNFLT was significantly lower in eyes of AD compared to those of ED (area under the receiver operating characteristic [AUROC] curve: 0.85 …
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