作者
Cleodice Alves Martins, Ana Karina Teixeira da Cunha França, Raimunda Sheyla Carneiro Dias, Rayanna Cadilhe de Oliveira Costa, Antônio Pedro Leite Lemos, Alcione Miranda dos Santos, Elane Viana Hortegal, Dyego José de Araújo Brito
发表日期
2020/9/30
期刊
Revista da Associação Médica Brasileira
卷号
66
期号
9
页码范围
1235-1240
出版商
Associação Médica Brasileira
简介
INTRODUCTION
Sarcopenia is characterized by the involuntary loss of lean body mass associated with a progressive reduction of muscle strength.
OBJECTIVE
To determine the prevalence of sarcopenia in kidney transplant recipients and its association with the determining factors that control muscle homeostasis.
METHODS
We evaluated renal transplant recipients undergoing follow-up at the University Hospital of the Federal University of Maranhão from June 2017 to July 2018 and who met the inclusion criteria. Sarcopenia was defined according to the European criteria. The skeletal muscle mass index was measured by dual-energy radiological absorptiometry; the values <7,26 kg/m2 for men and <5,5 kg/m2 for women were adopted for muscle depletion. For handgrip strength, values of <30 kg for men and <20 kg for women were considered as reduced muscle strength. In both sexes, the cutoff point for walking speed was <0,8 m/s.
RESULTS
We evaluated 83 renal transplant recipients with a mean age of 48.8 ± 12,1 years and predominantly males (57,8%). The prevalence of sarcopenia was 19,3%. Among individuals without sarcopenia, 17,9% had a decrease in handgrip strength and 40,3% has altered gait speed.
DISCUSSION
Individuals submitted to renal transplant may develop sarcopenia while still young and already present altered muscle function and strength even before the depletion of lean body mass.
CONCLUSION
Early diagnosis may allow the prevention of sarcopenia and provide a better quality of life …
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