作者
Yoosoo Chang, Bo-Kyoung Kim, Kyung Eun Yun, Juhee Cho, Yiyi Zhang, Sanjay Rampal, Di Zhao, Hyun-Suk Jung, Yuni Choi, Jiin Ahn, João AC Lima, Hocheol Shin, Eliseo Guallar, Seungho Ryu
发表日期
2014/6/24
期刊
Journal of the American College of Cardiology
卷号
63
期号
24
页码范围
2679-2686
出版商
American College of Cardiology Foundation
简介
Objectives
The purpose of this study was to compare the coronary artery calcium (CAC) scores of metabolically-healthy obese (MHO) and metabolically healthy normal-weight individuals in a large sample of apparently healthy men and women.
Background
The risk of cardiovascular disease among obese individuals without obesity-related metabolic abnormalities, referred to as MHO, is controversial.
Methods
We conducted a cross-sectional study of 14,828 metabolically-healthy adults with no known cardiovascular disease who underwent a health checkup examination that included estimation of CAC scores by cardiac tomography. Being metabolically healthy was defined as not having any metabolic syndrome component and having a homeostasis model assessment of insulin resistance <2.5.
Results
MHO individuals had a higher prevalence of coronary calcification than normal weight subjects. In multivariable …
学术搜索中的文章
Y Chang, BK Kim, KE Yun, J Cho, Y Zhang, S Rampal… - Journal of the American College of Cardiology, 2014