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Although LOW BACK PAIN (LBP) represents a significant OCCUPATION al problem for hospital NURSE s, few investigations target NURSE s for LOW BACK PAIN and its association with the personal and work-related factors in Iran. This cross sectional study was performed on 245 nursing personnel (registered NURSE s, nursing aides, operating room technicians, anesthesiology technicians) working full time for at least 1 month at 4 hospitals. Data were collected by modified Nordic questionnaire and interview followed by clinical examination. X2, Mantel and logistic regression statistical tests were used. The 12-month period-prevalence of LBP was 49.9%(95% CI; 43-55/8). In this study 51 (21/7%) males and 184 (78/3%) females participated that mean age of them was 32 years. The prevalence of back pain increased with increasing age. There was no differences between the sexes, but more prevalence was observed in the married ones than singles. Odds ratio of LBP was increased 2/2 times with BMI higher than 27kg/m2. In this study the relationship between cumulative duration of employment in nursing job, duration of employment in present ward and manual handling and back pain was significant statistically. LBP is high among NURSE s. For prevention of LBP, ergonomic program, lifting team, correct lifting technique and wider research with taking into account LBP psychosocial factors and work task are suggested.