作者
Aline I Moser, Esther Kuenzli, Thomas Büdel, Edgar I Campos-Madueno, Odette J Bernasconi, Susan DeCrom-Beer, Barbara Jakopp, Ali Haji Mohammed, Nadir Khatib Hassan, Jan Fehr, Jakob Zinsstag, Christoph Hatz, Andrea Endimiani
发表日期
2021/2
期刊
Journal of Antimicrobial Chemotherapy
卷号
76
期号
2
页码范围
330-337
出版商
Oxford University Press
简介
Objectives
Many travellers to low-income countries return home colonized at the intestinal level with extended-spectrum cephalosporin-resistant (ESC-R) and/or colistin-resistant (CST-R) Escherichia coli (Ec) strains. However, nothing is known about the local sources responsible for the transmission of these pathogens to the travellers.
Methods
We compared the ESC-R- and CST-R-Ec strains found in the pre- (n = 23) and post-trip (n = 37) rectal swabs of 37 travellers from Switzerland to Zanzibar with those (i) contemporarily isolated from local people, poultry, retailed chicken meat (n = 31), and (ii) from other sources studied in the recent past (n = 47). WGS and core-genome analyses were implemented.
Results
Twenty-four travellers returned colonized with ESC-R- (n = 29) and/or CST-R- (n = 8) Ec strains. Almost all ESC-R-Ec were CTX-M-15 …
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AI Moser, E Kuenzli, T Büdel, EI Campos-Madueno… - Journal of Antimicrobial Chemotherapy, 2021