作者
James A Dunbar, Andrea L Hernan, Edward D Janus, Erkki Vartiainen, Tiina Laatikainen, Vincent L Versace, John Reynolds, James D Best, Timothy C Skinner, Sharleen L O'Reilly, Kevin P Mc Namara, Elizabeth Stewart, Michael Coates, Catherine M Bennett, Rob Carter
发表日期
2015/10/1
期刊
BMJ Open Diabetes Research and Care
卷号
3
期号
1
页码范围
e000131
出版商
BMJ Specialist Journals
简介
Objective
To assess effectiveness and implementability of the public health programme Life! Taking action on diabetes in Australian people at risk of developing type 2 diabetes.
Research design and methods
Melbourne Diabetes Prevention Study (MDPS) was a unique study assessing effectiveness of Life! that used a randomized controlled trial design. Intervention participants with AUSDRISK score ≥15 received 1 individual and 5 structured 90 min group sessions. Controls received usual care. Outcome measures were obtained for all participants at baseline and 12 months and, additionally, for intervention participants at 3 months. Per protocol set (PPS) and intention to treat (ITT) analyses were performed.
Results
PPS analyses were considered more informative from our study. In PPS analyses, intervention participants significantly improved in weight (−1.13 kg, p=0.016), waist circumference (−1.35 cm, p=0 …
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JA Dunbar, AL Hernan, ED Janus, E Vartiainen… - BMJ Open Diabetes Research and Care, 2015