作者
Diddier Prada, Andrea A Baccarelli, Mary Beth Terry, Leonora Valdéz, Paula Cabrera, Allan Just, Itai Kloog, Haydee Caro, Claudia García-Cuellar, Yesennia Sánchez-Pérez, Rodrigo Cruz, Jose Diaz-Chávez, Carlo Cortés, Delia Pérez, Abelardo Meneses-García, David Cantú-de-León, Luis A Herrera, Enrique Bargalló
发表日期
2021/7
期刊
Breast cancer research and treatment
卷号
188
页码范围
525-533
出版商
Springer US
简介
Purpose
Increasingly epidemiological evidence supports that environmental factors are associated with breast cancer (BC) outcomes after a BC diagnosis. Although evidence suggests that air pollution exposure is associated with higher mortality in women with BC, studies investigating potential mechanisms have been lacking.
Methods
We evaluated women with BC (N = 151) attended at the National Cancer Institute–Mexico from 2012 to 2015. We calculated 1-year average exposures to particulate matter < 2.5 μm (PM2.5) at home address before diagnosis. We used linear and logistic regression models to determine the associations between PM2.5 exposure and BC aggressiveness (tumor size, molecular phenotype).
Results
Average annual PM2.5 exposure of this population was 23.0 μg/m3 [standard deviation …
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D Prada, AA Baccarelli, MB Terry, L Valdéz, P Cabrera… - Breast cancer research and treatment, 2021