作者
Silvia Budday, Gerhard Sommer, Johannes Haybaeck, Paul Steinmann, Gerhard A Holzapfel, Ellen Kuhl
发表日期
2017/9/15
期刊
Acta biomaterialia
卷号
60
页码范围
315-329
出版商
Elsevier
简介
The rheology of ultrasoft materials like the human brain is highly sensitive to regional and temporal variations and to the type of loading. While recent experiments have shaped our understanding of the time-independent, hyperelastic response of human brain tissue, its time-dependent behavior under various loading conditions remains insufficiently understood. Here we combine cyclic and relaxation testing under multiple loading conditions, shear, compression, and tension, to understand the rheology of four different regions of the human brain, the cortex, the basal ganglia, the corona radiata, and the corpus callosum. We establish a family of finite viscoelastic Ogden-type models and calibrate their parameters simultaneously for all loading conditions. We show that the model with only one viscoelastic mode and a constant viscosity captures the essential features of brain tissue: nonlinearity, pre-conditioning …
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S Budday, G Sommer, J Haybaeck, P Steinmann… - Acta biomaterialia, 2017