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This study aimed to explore the role of resilience for developing the self-efficacy among chemistry students in Pakistan. Self-efficacy refers to an individual's belief in their ability to perform a specific task or achieve a particular goal. Resilience refers to an individual's ability to bounce back from adversity and overcome challenges. The present qualitative study directing interpretivism as paradigm and adopted the qualitative research design. The chemistry teachers were the population of the research study. Four (04) participants were selected from the population on the basis of purposive sampling. Semi-structured interviews were conducted for the collection of data; as semi-structured interviews were used for deep and in-depth study. The researcher used the intelligent transcription for the purpose of the data collection. The results of the study showed that the nature of chemistry education is predominantly theoretical, with a lack of practical applications. This presents a challenge for students in understanding the subject matter. The role of teachers in chemistry education is also significant. Strategies for improving chemistry education include creating positive change in the subject, improving student understanding of chemistry, and developing innovative teaching methodologies. It is also essential to help students develop the ability to recover from setbacks and build their confidence through positive reinforcement.