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Man is always searching for inventions and discoveries; his restless nature always inspires and compels him/her to think more and more about the overcoming of curiosity. In this perspective, they questions themselves that what is a function of things? What is the reality behind the things? How we overcome the issues, problems and dilemmas? How confidence level developed in the personals (Emmert‐Streib et al., 2020; Green, 2016). The conception of self efficacy is old, introuduced by Bundura in 1977 (Elgendi et al., 2021; Maciejewski et al., 2000) that was derived from his book published on social work in 1963 (Bandura & Walters, 1963) but the concept of resilience is introduced in education recently; and is taken from psychology and sociology (Mirza &Arif, 2018; Van Bavel et al., 2020; Woodroof, 1990). Primarily, the concept of resilience was used in industry and project management; in education, the scientific study regarding resilience in children was made in the 1960s (Masten& Reed, 2002; PeConga et al., 2020; Tusaie& Dyer, 2004; Vernon, 2004). Therefore, this research work is formulated to find the relationship between resilience and self-efficacy of 10thgrade chemistry students in district Lahore, Pakistan.