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OBJECTIVE. The purpose of our study was to evaluate the feasibility of preserving image quality during CT colonography (CTC) using a reduced radiation dose with adaptive statistical iterative reconstruction (ASIR).

MATERIALS AND METHODS. A proven colon phantom was imaged at standard dose settings (50 mAs) and at reduced doses (10–40 mAs) using six different ASIR levels (0–100%). We assessed 2D and 3D image quality and noise to determine the optimal dose and ASIR setting. Eighteen patients were then scanned with a standard CTC dose (50 mAs) in the supine position and at a reduced dose of 25 mAs with 40% ASIR in the prone position. Three radiologists blinded to the scanning techniques assessed 2D and 3D image quality and noise at three different colon locations. A score difference of ≥ 1 was considered clinically important. Actual noise measures were compared between the standard …