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A 61-year-old uremic male under hemodialysis underwent Tc-99m sestamibi scintigraphy due to suspicious secondary hyperparathyroidism. The images showed increased uptake in the right forearm, left shoulder, right knee and, to a lesser extent, in the left hip and the right thigh. Subsequent Tc-99m MDP bone scintigraphy and x-ray studies revealed intense extraosseous uptake and calcified masses in areas corresponding to those found in Tc-99m sestamibi scintigraphy, suggesting tumoral calcinoses. We demonstrate the rare case in which Tc-99m sestamibi was taken up by tumoral calcinoses.