作者
Christopher J Lettieri, Anita A Shah, Aaron B Holley, William F Kelly, Audrey S Chang, Stuart A Roop, CPAP ASAP (CPAP Promotion and Prognosis—The Army Sleep Apnea Program) Trial
发表日期
2009/11/17
期刊
Annals of internal medicine
卷号
151
期号
10
页码范围
696-702
出版商
American College of Physicians
简介
Background
Adherence to short-term continuous positive airway pressure (CPAP) may predict long-term use. Unfortunately, initial CPAP intolerance may lead to poor adherence or abandonment of therapy.
Objective
To determine whether a short course of eszopiclone at the onset of therapy improves long-term CPAP adherence more than placebo in adults with obstructive sleep apnea.
Design
Parallel randomized, placebo-controlled trial from March 2007 to December 2008. Randomization, maintained and concealed centrally by pharmacy personnel, was computer-generated using fixed blocks of 10. Referring physicians, investigators, and patients were blinded to the treatment assignment until after the final data were collected. (ClinicalTrials.gov registration number: NCT00612157)
Setting
Academic …
学术搜索中的文章
CJ Lettieri, AA Shah, AB Holley, WF Kelly, AS Chang… - Annals of internal medicine, 2009