作者
Sabbir T Rahman, Mary Waterhouse, Briony Duarte Romero, Catherine Baxter, Dallas English, David A Mackey, Peter R Ebeling, Bruce K Armstrong, Donald SA McLeod, Gunter Hartel, Rachel L O’Connell, Jolieke C van der Pols, Alison J Venn, Penelope M Webb, David C Whiteman, Rachel E Neale
发表日期
2023/3/1
期刊
Ophthalmology
卷号
130
期号
3
页码范围
313-323
出版商
Elsevier
简介
Purpose
Observational studies suggest that higher serum 25-hydroxy vitamin D (25(OH)D) concentration may be associated with lower risk of cataract. However, no randomized controlled trials have assessed the effect of vitamin D supplementation on the incidence of cataract. We aimed to assess whether vitamin D supplementation reduces the incidence of cataract surgery.
Design
We conducted an ancillary study of the D-Health Trial, a randomized, double-masked, placebo-controlled trial of monthly vitamin D conducted from 2014 through 2020 within the Australian general population.
Participants
We invited 421 207 men and women 60 to 84 years of age to participate; including an additional 1896 volunteers, 40 824 expressed interest. Those with hypercalcemia, hyperparathyroidism, kidney stones, osteomalacia, or sarcoidosis or those who were taking more than 500 international units (IU) supplemental vitamin …
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ST Rahman, M Waterhouse, BD Romero, C Baxter… - Ophthalmology, 2023