作者
Soyeon Jeon, Songmi Kim, Man Hwan Oh, Ping Liang, Wanxiangfu Tang, Kyudong Han
发表日期
2021/10
期刊
Genes & Genomics
卷号
43
期号
10
页码范围
1133-1141
出版商
Springer Singapore
简介
Background
Long interspersed element-1 (LINE-1 or L1) is the most abundant retrotransposons in the primate genome. They have approximately 520,000 copies and make up ~ 17% of the primate genome. Full-length L1s can mobilize to a new genomic location using their enzymatic machinery. Gorilla is the second closest species to humans after the chimpanzee, and human-gorilla split 7–12 million years ago. The gorilla genome provides an opportunity to explore primate origins and evolution.
Objective
L1s have contributed to genome diversity and variations during primate evolution. This study aimed to identify gorilla-specific L1s using a more recent version of the gorilla reference genome (Mar. 2016 GSMRT3/gorGor5).
Methods
We collected gorilla-specific L1 candidates through computational analysis and manual inspection. L1Xplorer was used to identify whether full-length gorilla-specific L1s were intact. In …
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