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In this paper, retrieval accuracy of different types of pulmonary nodules is studied. The trainee radiologists could enrich their knowledge using the visual information of the retrieved nodules. In the proposed retrieval system, the pulmonary nodules are segmented using a semi-automated technique. Several 3D features are explored to improve the performance of the proposed retrieval system. A set of relevant shape and texture features is determined for efficient representation of the nodules in the feature space. The proposed CBIR system is validated on a data set of 542 nodules of Lung Image Database Consortium and Image Database Resource Initiative (LIDC/IDRI). The nodules with composite rank of malignancy “1”, “2” are considered as benign and “4”, “5” are considered as malignant. Considering top five retrieved images, the precision of the proposed retrieval system are 84.76%, 80.75%, and 80.34% for …