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Based on experiences and the literature, our objective is to provide practical suggestions for performing endoscopy in the setting of the novel coronavirus-19 (COVID-19) pandemic. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), referred to as COVID-19, has become a global pandemic. Human-to-human transmission occurs through respiratory secretions, aerosols, feces, and contaminated environmental surfaces. 1, 2 Transmission can occur in both symptomatic and asymptomatic individuals. 3 Viable virus particles can be detected in aerosols up to 3 hours after aerosolization and up to 3 days on surfaces. 4 A recent publication suggests that undocumented infections were the source of a substantial majority of documented cases. 5 The risk of infection to healthcare workers is significant: In one of the earliest documentations of infection in Wuhan, 29% of patients (40/138) were healthcare workers …