作者
Faeq Husain‐Syed, Hermann‐Josef Gröne, Birgit Assmus, Pascal Bauer, Henning Gall, Werner Seeger, Ardeschir Ghofrani, Claudio Ronco, Horst‐Walter Birk
发表日期
2021/2
来源
ESC heart failure
卷号
8
期号
1
页码范围
183-203
简介
Venous congestion has emerged as an important cause of renal dysfunction in patients with cardiorenal syndrome. However, only limited progress has been made in differentiating this haemodynamic phenotype of renal dysfunction, because of a significant overlap with pre‐existing renal impairment due to long‐term hypertension, diabetes, and renovascular disease. We propose congestive nephropathy (CN) as this neglected clinical entity. CN is a potentially reversible subtype of renal dysfunction associated with declining renal venous outflow and progressively increasing renal interstitial pressure. Venous congestion may lead to a vicious cycle of hormonal activation, increased intra‐abdominal pressure, excessive renal tubular sodium reabsorption, and volume overload, leading to further right ventricular (RV) stress. Ultimately, renal replacement therapy may be required to relieve diuretic‐resistant congestion …
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