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The lacrimal gland is an important part of lacrimal apparatus that plays an essential role in eye health. In this research, anatomical and histological structures of lacrimal glands of Lori sheep were evaluated. For this purpose, thirty healthy and mature Lori sheep were selected in slaughterhouse and then lacrimal glands removed. After anatomical and biometrical evaluation, lacrimal glands were fixed and processed for histological sectioning and then sections stained with H&E, Alcian blue and Periodic acid Schiff methods. The results showed that in this species the lacrimal gland lies in dorso-lateral aspect of orbit on the eyeball. The lacrimal gland is surrounded with a connective tissue containing adipose tissue. The gland shows an irregular-rounded to oval shape and pale brown in color. The mean weight, length, width and thickness of the gland were 1.48±0.3 gr, 26.98±0.37 mm, 20.11±0.31 mm and 3.58±0.7 mm …