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The North American pawpaw (Asimina triloba L.) fruit is an underutilized specialty crop native to North America. Due to the short shelf life of the fruit, it has remained underutilized and uncommercialized. Over the years, various studies have found that it contains many valuable bioactive compounds. However, to date, there has been no review of the studies done to consolidate these findings and highlight the research gaps to create opportunities for future research.

Bioactive compounds are high-value compounds with a wide range of applications. This paper reviews the studies done on the bioactive compounds in the tissues of the fruit (peels, seeds, and pulp) in the last 30 years to provide the current state of knowledge on the bioactive constituents of the North American pawpaw fruit. This review points out the gaps in the available research to pave the way for further studies on the …