作者
Mia Hashibe, Paul Brennan, Simone Benhamou, Xavier Castellsague, Chu Chen, Maria Paula Curado, Luigino Dal Maso, Alexander W Daudt, Eleonora Fabianova, Victor Wünsch-Filho, Silvia Franceschi, Richard B Hayes, Rolando Herrero, Sergio Koifman, Carlo La Vecchia, Philip Lazarus, Fabio Levi, Dana Mates, Elena Matos, Ana Menezes, Joshua Muscat, Jose Eluf-Neto, Andrew F Olshan, Peter Rudnai, Stephen M Schwartz, Elaine Smith, Erich M Sturgis, Neonilia Szeszenia-Dabrowska, Renato Talamini, Qingyi Wei, Deborah M Winn, David Zaridze, Witold Zatonski, Zuo-Feng Zhang, Julien Berthiller, Paolo Boffetta
发表日期
2007/5/16
期刊
Journal of the National Cancer Institute
卷号
99
期号
10
页码范围
777-789
出版商
Oxford University Press
简介
Background
At least 75% of head and neck cancers are attributable to a combination of cigarette smoking and alcohol drinking. A precise understanding of the independent association of each of these factors in the absence of the other with the risk of head and neck cancer is needed to elucidate mechanisms of head and neck carcinogenesis and to assess the efficacy of interventions aimed at controlling either risk factor.
Methods
We examined the extent to which head and neck cancer is associated with cigarette smoking among never drinkers and with alcohol drinking among never users of tobacco. We pooled individual-level data from 15 case–control studies that included 10244 head and neck cancer case subjects and 15227 control subjects, of whom 1072 case subjects and 5775 control subjects were never users of tobacco and 1598 case subjects and 4051 control …
引用总数
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M Hashibe, P Brennan, S Benhamou, X Castellsague… - Journal of the National Cancer Institute, 2007