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In the era of ubiquitous intelligence, the Internet of Things (IoT) holds the promise as a breakthrough technology to enable diverse applications that benefit societal problems. Yet interconnecting myriad heterogeneous IoT devices across various application domains remain a security challenge. Decentralized technology has recently emerged as a powerful primitive in building distributed applications to facilitate secure transactions between mutually distrustful parties in a trustworthy manner. Unfortunately, these decentralized protocols demand computing resources and power far beyond the reach of resource-constrained IoT devices, preventing the full adoption of distributed consensus platform in the IoT setting. In this article, we address the key bottleneck to enable blockchain in resource-constrained IoT devices. We propose a lightweight implementation of proof-of-work (PoW) mining with reconfigurable hardware …