作者
Faidra Laskou, Nicholas R Fuggle, Harnish P Patel, Karen Jameson, Cyrus Cooper, Elaine Dennison
发表日期
2022/2
期刊
Journal of cachexia, sarcopenia and muscle
卷号
13
期号
1
页码范围
220-229
简介
Background
Ageing is commonly associated with sarcopenia (SP) and osteoporosis (OP), both of which are associated with disability, impaired quality of life, and mortality. The aims of this study were to explore the relationships between SP, OP, frailty, and multimorbidity in community‐dwelling older adults participating in the Hertfordshire Cohort Study (HCS) and to determine whether coexistence of OP and SP was associated with a significantly heavier health burden.
Methods
At baseline, 405 participants self‐reported their comorbidities. Cut‐offs for low grip strength and appendicular lean mass index were used according to the EWSGOP2 criteria to define SP. OP was diagnosed when T‐scores of < −2.5 were present at the femoral neck or the participant reported use of the anti‐OP medications including hormone replacement therapy (HRT), raloxifene, or bisphosphonates. Frailty was defined using the …
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