作者
Navkaranbir S Bajaj, Amitoj Singh, Wunan Zhou, Ankur Gupta, Kana Fujikura, Christina Byrne, Hendrik J Harms, Michael T Osborne, Paco Bravo, Efstathia Andrikopolou, Sanjay Divakaran, Courtney F Bibbo, Jon Hainer, Hicham Skali, Viviany Taqueti, Michael Steigner, Sharmila Dorbala, David M Charytan, Sumanth D Prabhu, Ron Blankstein, Rahul C Deo, Scott D Solomon, Marcelo F Di Carli
发表日期
2020/1/7
期刊
Circulation
卷号
141
期号
1
页码范围
21-33
出版商
Lippincott Williams & Wilkins
简介
Background
Cardiac dysfunction and cardiovascular events are prevalent among patients with chronic kidney disease without overt obstructive coronary artery disease, but the mechanisms remain poorly understood. Coronary microvascular dysfunction has been proposed as a link between abnormal renal function and impairment of cardiac function and cardiovascular events. We aimed to investigate the relations between chronic kidney disease, coronary microvascular dysfunction, cardiac dysfunction, and adverse cardiovascular outcomes.
Methods
Patients undergoing cardiac stress positron emission tomography, echocardiogram, and renal function ascertainment at Brigham and Women’s Hospital were studied longitudinally. Patients free of overt coronary (summed stress score <3 and without a history of ischemic heart disease), valvular, and end-organ disease were followed up for the adverse composite …
学术搜索中的文章
NS Bajaj, A Singh, W Zhou, A Gupta, K Fujikura… - Circulation, 2020