作者
Debra E Weese-Mayer, Juliann M Di Fiore, Douglas E Lake, Anna Maria Hibbs, Nelson Claure, Jiaxing Qiu, Namasivayam Ambalavanan, Eduardo Bancalari, James S Kemp, Amanda M Zimmet, John L Carroll, Richard J Martin, Katy N Krahn, Aaron Hamvas, Sarah J Ratcliffe, Narayanan Krishnamurthi, Premananda Indic, Alaleh Dormishian, Phyllis A Dennery, J Randall Moorman
发表日期
2024/3
期刊
Pediatric research
卷号
95
期号
4
页码范围
1060-1069
出版商
Nature Publishing Group US
简介
Background
In extremely preterm infants, persistence of cardioventilatory events is associated with long-term morbidity. Therefore, the objective was to characterize physiologic growth curves of apnea, periodic breathing, intermittent hypoxemia, and bradycardia in extremely preterm infants during the first few months of life.
Methods
The Prematurity-Related Ventilatory Control study included 717 preterm infants <29 weeks gestation. Waveforms were downloaded from bedside monitors with a novel sharing analytics strategy utilized to run software locally, with summary data sent to the Data Coordinating Center for compilation.
Results
Apnea, periodic breathing, and intermittent hypoxemia events rose from day 3 of life then fell to near-resolution by 8–12 weeks of age. Apnea/intermittent hypoxemia were inversely correlated with gestational age, peaking at 3–4 weeks of age. Periodic breathing was positively correlated …
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DE Weese-Mayer, JM Di Fiore, DE Lake, AM Hibbs… - Pediatric research, 2024