作者
Wenjie Li, Miranda T Schram, Tos TJM Berendschot, Carroll AB Webers, Abraham A Kroon, Carla JH van der Kallen, Ronald MA Henry, Nicolaas C Schaper, Fan Huang, Behdad Dashtbozorg, Tao Tan, Jiong Zhang, Samaneh Abbasi-Sureshjani, Bart M ter Haar Romeny, Coen DA Stehouwer, Alfons JHM Houben
发表日期
2020/7
期刊
Diabetologia
卷号
63
页码范围
1408-1417
出版商
Springer Berlin Heidelberg
简介
Aims/hypothesis
Retinal microvascular diameters are biomarkers of cardio-metabolic risk. However, the association of (pre)diabetes with retinal microvascular diameters remains unclear. We aimed to investigate the association of prediabetes (impaired fasting glucose or impaired glucose tolerance) and type 2 diabetes with retinal microvascular diameters in a predominantly white population.
Methods
In a population-based cohort study with oversampling of type 2 diabetes (N = 2876; n = 1630 normal glucose metabolism [NGM], n = 433 prediabetes and n = 813 type 2 diabetes, 51.2% men, aged 59.8 ± 8.2 years; 98.6% white), we determined retinal microvascular diameters (measurement unit as measured by retinal health information and notification system [RHINO] software) and glucose metabolism status (using OGTT). Associations were assessed with multivariable regression analyses adjusted for …
学术搜索中的文章
W Li, MT Schram, TTJM Berendschot, CAB Webers… - Diabetologia, 2020