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The El Niño/Southern Oscillation (ENSO) is the dominant mode of interannual climate variability on Earth, alternating between anomalously warm (El Niño) and cold (La Niña) conditions in the tropical Pacific at intervals of 2–8 years^,. The amplitude of ENSO variability affects the occurrence and predictability of climate extremes around the world^,, but our ability to detect and predict changes in ENSO amplitude is limited by the fact that the instrumental record is too short to characterize its natural variability^,,,. Here we use the North American Drought Atlas^,—a database of drought reconstructions based on tree-ring records—to produce a continuous, annually resolved record of ENSO variability over the past 1,100 years. Our record is in broad agreement with independent, ENSO-sensitive proxy records in the Pacific and surrounding regions. Together, these records indicate that ENSO amplitude exhibits a quasi-regular …