作者
Tommy Nyberg, Katherine A Twohig, Ross J Harris, Shaun R Seaman, Joe Flannagan, Hester Allen, Andre Charlett, Daniela De Angelis, Gavin Dabrera, Anne M Presanis
发表日期
2021/6/15
期刊
bmj
卷号
373
出版商
British Medical Journal Publishing Group
简介
Objective
To evaluate the relation between diagnosis of covid-19 with SARS-CoV-2 variant B.1.1.7 (also known as variant of concern 202012/01) and the risk of hospital admission compared with diagnosis with wild-type SARS-CoV-2 variants.
Design
Retrospective cohort analysis.
Setting
Community based SARS-CoV-2 testing in England, individually linked with hospital admission data.
Participants
839 278 patients with laboratory confirmed covid-19, of whom 36 233 had been admitted to hospital within 14 days, tested between 23 November 2020 and 31 January 2021 and analysed at a laboratory with an available TaqPath assay that enables assessment of S-gene target failure (SGTF), a proxy test for the B.1.1.7 variant. Patient data were stratified by age, sex, ethnicity, deprivation, region of residence, and date of positive test.
Main outcome measures
Hospital admission between one and 14 days after the first …
学术搜索中的文章
T Nyberg, KA Twohig, RJ Harris, SR Seaman… - bmj, 2021