作者
Francesca Assogna, Clelia Pellicano, Luca Cravello, Cinzia Savini, Lucia Macchiusi, Mariangela Pierantozzi, Alessandro Stefani, Bruno Mercuri, Carlo Caltagirone, Francesco E Pontieri, Gianfranco Spalletta
发表日期
2019/12
期刊
Brain and Behavior
卷号
9
期号
12
页码范围
e01448
简介
Introduction
Phenotypic variants of progressive supranuclear palsy (PSP) are all characterized by the combination of motor symptoms of parkinsonism with a number of neuropsychiatric and cognitive disorders. Despite the strong effort in characterizing these features in PSP, alexithymia and anhedonia have not been investigated at present. Here, we aimed at investigating the qualitative and quantitative differences of alexithymia and anhedonia in the two more frequent variants of PSP, Richardson's syndrome (PSP‐RS) and PSP with predominant parkinsonism (PSP‐P) compared to Parkinson's disease (PD) patients recruited within 24 months after the onset of motor symptoms.
Methods
One hundred fifty‐five PD, 11 PSP‐P, and 14 PSP‐RS patients underwent clinical, neuropsychiatric, and neuropsychological evaluations. Alexithymia was assessed using the Toronto Alexithymia Scale‐20 item (TAS‐20), and …
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F Assogna, C Pellicano, L Cravello, C Savini… - Brain and Behavior, 2019