作者
Sheng-Hung Chen, Yu-Fen Li, Hsueh-Chou Lai, Jung-Ta Kao, Cheng-Yuan Peng, Po-Heng Chuang, Wen-Pang Su, I-Ping Chiang
发表日期
2012/12
期刊
BMC gastroenterology
卷号
12
页码范围
1-13
出版商
BioMed Central
简介
Background
Previous research has shown variation in the effects of patient factors, including hepatic necroinflammatory activity, on liver stiffness measurement (LSM). This prospective study attempts to identify explanatory factors for LSM in patients with chronic hepatitis C (CHC) using acoustic radiation force impulse (ARFI) technology.
Methods
A cohort of 127 Taiwanese patients with CHC underwent ARFI LSM and immediate percutaneous liver biopsy. This study compares the concurrent diagnostic performances of LSM and FibroTest using receiver operating characteristic (ROC) curves. Three multiple linear regression models were used to evaluate the significance of concurrent patient factors in explaining LSM.
Results
To classify METAVIR fibrosis (F) stages, the areas under ROC curves (AUCs) were ARFI LSM, 0 …
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