作者
Sheng-Hung Chen, Hsueh-Chou Lai, I-Ping Chiang, Wen-Pang Su, Chia-Hsin Lin, Jung-Ta Kao, Po-Heng Chuang, Wei-Fan Hsu, Hung-Wei Wang, Hung-Yao Chen, Guan-Tarn Huang, Cheng-Yuan Peng
发表日期
2020/1/1
期刊
Clinical Infectious Diseases
卷号
70
期号
1
页码范围
114-122
出版商
Oxford University Press
简介
Background
Data on noninvasive liver fibrosis staging after viral eradication are unclear. This histology-based study validated the performance of liver stiffness (LS) measurements after viral eradication.
Methods
Consecutive participants with chronic hepatitis C (CHC) who received concomitant LS measurements through acoustic radiation force impulse (ARFI) elastography and percutaneous liver biopsy were prospectively screened and analyzed.
Results
Of the 644 patients, 521 (80.9%) underwent a biopsy at treatment baseline, and the remaining 123 (19.1%) underwent a biopsy at 3 years (median; interquartile range, 0.1) after the sustained virological response (SVR) to pegylated interferon–based and direct-acting antiviral treatments. The proportions of histological fibrosis stages did not differ significantly between the pretreatment and post-SVR groups …
学术搜索中的文章
SH Chen, HC Lai, IP Chiang, WP Su, CH Lin, JT Kao… - Clinical Infectious Diseases, 2020